hrp0089p1-p095 | Fat, Metabolism and Obesity P1 | ESPE2018

Variation of Circulating Brain-Derived Neurotrophic Factor According to Gender, Body Mass Index and Metabolic Syndrome Parameters in Adolescents

Bacopoulou Flora , Tsitsimpikou Christina , Mantzou Aimilia , Apostolaki Despoina , Darviri Christina , Efthymiou Vasiliki

Background: Brain-derived neurotrophic factor (BDNF) plays a role in the central regulation of energy balance and has been associated with body mass index (BMI).Objective: The aim of this study was to investigate potential differences in serum BDNF concentrations in adolescents by gender and BMI, as well as possible correlations of circulating BDNF with the adolescentsÂ’ characteristics of metabolic syndrome.Methods: Study part...

hrp0089p2-p134 | Fat, Metabolism and Obesity P2 | ESPE2018

Serum Spexin Concentrations in Adolescent Females with Metabolic Syndrome, Polycystic Ovary Syndrome and Anorexia Nervosa

Bacopoulou Flora , Efthymiou Vasiliki , Apostolaki Despoina , Tsitsimpikou Christina , Tsarouhas Konstantinos , Darviri Christina , Mantzou Aimilia

Background: Spexin is a novel hormone that may potentially impact food intake, weight regulation and body adiposity. Circulating spexin has been associated with obesity and insulin resistance indices in women.Objective: The aim of this study was to determine serum spexin concentrations in adolescent females with metabolic syndrome, with polycystic ovary syndrome (PCOS), with anorexia nervosa as well as in healthy controls, and explore possible relationsh...